We have extensive experience in design and execution of pre-clinical studies for drug development within oncology and immuno-oncology. We can perform studies with cell line based models as well as PDX models available through the START-MINERVA collaboration. Studies can be designed to take advantage of our capabilities of orthotopic and metastatic models, external radiation therapy, and advanced non-invasive imaging.
Subcutaneous xenograft models (rats and mice)
Targeted radionuclide therapy
Orthotopic xenograft models
Subcutaneous and orthotopic syngeneic models
PDX models, including orthotopic implantation
External radiation therapy
Optical (bioluminescence) imaging